The Study to Assess Long-term
Opioid Maintenance Effectiveness
SALOME is a clinical study that tests alternative treatments for people with chronic heroin addiction who are currently not benefiting sufficiently from available treatments such as oral methadone. SALOME compares two similar medications – diacetylmorphine, the active ingredient of heroin, and hydromorphone (HDM), a legal, licensed pain medication. This study will also test if those effectively treated with these two injectable medications can be successfully switched and retained to the oral formulations of the medications.