Smaller volume of split-dose bowel prep equal to conventional volume

A split 2-liter dose of bowel preparation before colonoscopy was similarly effective as a split 4-liter dose in a study presented at Digestive Disease Week. In a prospective, single-center noninferiority trial, researchers randomly assigned 317 adult patients referred for outpatient colonoscopy at St. Paul’s Hospital in Vancouver, Canada, to bowel preparation with split doses of either 4 liters of PegLyte (n=156) or 2 liters of PegLyte with 15 mg bisacodyl (n=161).

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