Text size: S M L XL

Study Objectives

The general objectives of this study were to determine whether:

1. he closely supervised provision of injectable hydromorphone is as effective as injectable diacetylmorphine in recruiting, retaining, and benefiting chronic, severely affected opioid-dependent individuals.

2. If the switch to the oral equivalent of hydromorphone and diacetylmorphine after six-months is as effective as the injection form.

SALOME had two separate aspects: provision of treatment and evaluation of outcomes. Both services were provided by different team members and in two different offices.

The health care providers did not have access to participants’ responses to the outcome evaluations. Nevertheless Clinic and Research worked together as one team for the whole study.