New drug may block sun-related skin ageing (Providence Health Care)

Scientists are developing a drug that could ultimately prevent the gradual ageing of the skin, which is mostly caused by sun exposure.

Researchers at the University of British Columbia and Providence Health Care in Canada have genetically engineered mice with less wrinkled skin, despite repeated exposure to wrinkle-inducing ultraviolet (UV) light.

The findings raise hope for a drug that would block the activity of Granzyme B in certain places, and thus prevent the ageing and deterioration of tissues that depend on collagen — not just skin, but blood vessels and lung passages, researchers said.

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