A drug to help stop wrinkles and aging? UBC scientists raising hopes (Providence Health Care)

A team of scientists at the University of British Columbia and Providence Health Care is raising hopes for a drug that will prevent aging and  wrinkles.

They have genetically engineered mice with less wrinkled skin despite repeated exposure to wrinkle-inducing UV light. This discovery occurred when UBC professor David Granville was investigating the role of Granzyme B in atherosclerosis and heart attacks. He and his team found that the mice being given this drug retained youthful-looking skin compared to normal aged skin.

They published the findings last week in Aging Cell, stating the drug would block the activity of Granzyme B in certain places, and therefore prevent the aging and deterioration of tissues that depend on collagen, including skin blood vessels and lung passages.

Amy Judd reports

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