St Paul's Hospital - Providence Health CareGeneral Surgery

Andrew Seal, M.D., M.Sc., F.R.C.S.C.

Andrew Seal, M.D., M.Sc.,  F.R.C.S.C.

Dr. Seal is Associate Professor of Surgery in the Department of Surgery at the University of British Columbia, Vancouver, BC, Canada. He graduated from Guy's Hospital Medical School in London, England in 1969. In 1979 he completed his general surgery residency at the University of British Columbia and obtained his Fellowship in the Royal College of Physicians and Surgeons of Canada.

From 1980 to 1981 Dr. Seal was a Visiting Scientist at the Centre for Ulcer Research and Education in Los Angeles. In July 1981 he returned to Vancouver and joined the Department of Surgery at UBC as a member of the active staff at the Health Sciences Centre Hospital on the UBC campus. He was appointed Associate Dean of Student Affairs in the Faculty of Medicine from 1994 to 1999 and on completion of his term became a visiting scholar at St. Catharine's College at Cambridge. He returned to UBC in 2000 and became a member of the Division of General Surgery at St Paul's Hospital in 2003.



Studies of (i) Massive small bowel resection; (ii) Colonic perfusion: effects on gastric and pancreatic secretion and gastrointestinal peptides. M.S. Thesis, University of London, 1980.


Seal AM: Derangements in intestinal function secondary to previous operation. In: The Physiologic Basis of Modern Surgical Care; Miller TA and Rowlands BJ (eds.). St. Louis, Missouri: C.V. Mosby, 1988.

Journals (Refereed Publications)

Seal AM, Debas HT: Colonic inhibition of gastric acid secretion in the dog. Gastroenterology 1980; 79:823-826.

Soon-Shiong P, Debas HT, Seal AM, Cheung G: Colonic inhibition of gastric acid secretion in man. Surg Forum 1980; 31:152-154.

Debas HT, Soon-Shiong P, Seal AM: Vagal cholinergic inhibition of food stimulated gastrin release. Surg Forum 1980; 31:167-169.

Debas HT, Seal AM, Cork C, Soon-Shiong P, Walsh JH: Vagal distribution for stimulation and inhibition of gastrin release. Surg Forum 1981; 32:143-145.

Seal AM: Appendicitis: a historical review. Can J Surg 1981; 24:427-433.

Seal AM, Debas HT, Reynolds C, Said SI, Taylor IL: Gastric and pancreatic hyposecretion following massive small bowel resection. Dig Dis Sci 1982; 27:117-123.

Seal AM, Yamada T, Debas HT, Hollinshead J, Osadchey B, Aponte G, Walsh J: Somatostatin-14 and Somatostatin-28: Clearance and potency on gastric function in dogs. Am J Physiol 1982; 243(Gastrointest Liver Physiol 6):G97-G102.

Debas HT, Taylor IL, Seal AM, Passaro E Jr: Evidence for vagus-dependent pancreatic-polypeptide-releasing factor in the antrum; studies with the autotransplanted dog pancreas. Surgery 1982; 92:309-314.

Seal AM: Hormones, secretions and adaptation in the short bowel syndrome. Proceedings of American Society for Parenteral and Enteral Nutrition, 6th Clinical Congress, 1982.

Atkinson KG, Bell GA, Seal AM: Inflammatory bowel disease - developments in surgery. BC Med Assoc J 1982; 24:287-288.

Debas H, Seal AM, Soon-Shiong P, Walsh J: Vagal control of gastrin release in the dog: pathways for stimulation and inhibition. Surgery 1984; 95:34-37.

Buchan AMJ, Seal AM, Debas HT: Increased antral G-cell number and gastrin content in dogs after massive small bowel resection. Dig Dis Sci 1985 (Mar); 30(3):236-239.

Seal AM, Meloche RM, Liu YQE, Buchan AMJ, Brown JC: The effects of monoclonal antibodies to somatostatin on somatostatin-induced and intestinal fat-induced inhibition of gastric acid secretion in the rat. Gastroenterology 92:1187-1192, 1987.

Sharp FR, Bell GA, Seal AM, Atkinson KG: Investigations of the anal sphincter before and after restorative proctocolectomy. Ann Surg 153:469-472, 1987.

Seal AM: Effects of monoclonal antibodies to somatostatin and neurotensin on intestinal fat-induced inhibition of gastric acid secretion in the rat. Am J Physiol 255:940-945, 1988.

Skarsgard ED, Atkinson KG, Bell GA, Pezim ME, Seal AM, Sharp FR: Function and quality of life results after ileal pouch surgery for chronic ulcerative colitis and familial polyposis. Am J Surg 157:467, 1989.

Hsiang YN, Seal AM: Massive small bowel resection in the rat. J Invest Surg 4:259-267, 1991.

Freeman HJ, Seal AM: Laminated Intestinal Calculi, A Rare Complication of Crohn's Desease. Can J. Gastro 8: No X, 1-4, 1994.

Freeman HJ, Seal AM: Survival from primary abdominal lymphoma presenting with a mass and obstructive jaundice. Can J Gastro 10:No 2, 89-92, 1997.